Anti-Cleaved-ADGRE5-S531 antibody (512-561 aa) (STJ90047)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CD97 beta at the amino acid range 512-561
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Adhesion G protein-coupled receptor E5-S531 (512-561 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADGRE5 |
| Gene ID | 976 |
| Uniprot ID | AGRE5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CD97 beta at the amino acid range 512-561 |
| Immunogen Region | 512-561 aa |
| Specificity | Cleaved-CD97 Beta (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97 Beta protein resulting from cleavage adjacent to S531. |
Additional Info
| Post Translational Modifications | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. |
| Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. |
| Protein Name | Adhesion G Protein-Coupled Receptor E5Leukocyte Antigen Cd97Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinAdhesion G Protein-Coupled Receptor E5 Subunit Alpha: SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E5 antibodyAnti-Leukocyte Antigen Cd97 antibodyAnti-Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta antibodyAnti-ADGRE5 antibodyAnti-CD97 antibody |
Information sourced from Uniprot.org