| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CLDN6 (121-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLDN6 |
| Gene ID: |
9074 |
| Uniprot ID: |
CLD6_HUMAN |
| Immunogen Region: |
121-220 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 121-220 of human Claudin 6 (NP_067018.2). |
| Immunogen Sequence: |
SGIVFVISGVLTLIPVCWTA HAIIRDFYNPLVAEAQKREL GASLYLGWAASGLLLLGGGL LCCTCPSGGSQGPSHYMARY STSAPAISRGPSEYPTKNYV |
| Tissue Specificity | Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines. |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space. (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells. |
| Protein Name | Claudin-6Skullin |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell JunctionTight JunctionCell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Claudin-6 antibodyAnti-Skullin antibodyAnti-CLDN6 antibodyAnti-UNQ757 antibodyAnti-PRO1488 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
