Anti-CLDN4/Claudin-4 antibody [SAA0509] {PE} (STJA0030811)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationPE
IsotypeIgG2ak
General Information
| Short Description | Mouse monoclonal Claudin-4 antibody for use in ELISA, FC and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0509 |
| Isotype | IgG2ak |
| Conjugation | PE |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | CLDN4 |
| Gene ID | 1364 |
| Uniprot ID | CLD4_HUMAN |
Additional Info
| Function | Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own. |
| Protein Name | Claudin-4Clostridium Perfringens Enterotoxin ReceptorCpe-RCpe-ReceptorWilliams-Beuren Syndrome Chromosomal Region 8 Protein |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell JunctionTight JunctionCell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Claudin-4 antibodyAnti-Clostridium Perfringens Enterotoxin Receptor antibodyAnti-Cpe-R antibodyAnti-Cpe-Receptor antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 8 Protein antibodyAnti-CLDN4 antibodyAnti-CPER antibodyAnti-CPETR1 antibodyAnti-WBSCR8 antibody |
Information sourced from Uniprot.org