| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Chloride Channel Protein 1 (889-988) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4237RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:2000-1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLCN1 |
| Gene ID: |
1180 |
| Uniprot ID: |
CLCN1_HUMAN |
| Immunogen Region: |
889-988 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 889-988 of human CLCN1 (NP_000074.3). |
| Immunogen Sequence: |
NTTSTRKSTGAPPSSAENWN LPEDRPGATGTGDVIAASPE TPVPSPSPEPPLSLAPGKVE GELEELELVESPGLEEELAD ILQGPSLRSTDEEDEDELIL |
| Tissue Specificity | Predominantly expressed in skeletal muscles. |
| Function | Voltage-gated chloride channel. Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (Probable). The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable). |
| Protein Name | Chloride Channel Protein 1Clc-1Chloride Channel Protein - Skeletal Muscle |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Chloride Channel Protein 1 antibodyAnti-Clc-1 antibodyAnti-Chloride Channel Protein - Skeletal Muscle antibodyAnti-CLCN1 antibodyAnti-CLC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
