| Host: | Rabbit |
| Applications: | IHC-p |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Claudin 18.2 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | IHC758 |
| Conjugation: | Unconjugated |
| Formulation: | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction: | Store at 2-8°C for up to 1 year. Do not freeze. |
| Specificity: | Tested and validated on pancreatic ductal adenocarcinoma tissue. |
| Background | The Claudin18.2 (CLDN18.2) protein, a splice variant of the membrane epithelial tight junction protein Claudin 18, is a promising pan-cancer target with limited expression in normal tissues. Studies demonstrates that the abnormal expression of CLDN18.2 is often observed during the occurrence and development of various primary tumors and metastases, including breast cancer, gastric cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small cell lung cancer. |
Information sourced from Uniprot.org
