| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CKAP4 (250-300 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
Ckap4 |
| Gene ID: |
216197 |
| Uniprot ID: |
CKAP4_MOUSE |
| Immunogen Region: |
250-300 aa |
| Specificity: |
Specific for CKAP4. |
| Immunogen: |
A synthetic peptide from aa region 250-300 of mouse CKAP4 conjugated to an immunogenic carrier protein was used as the antigen. |
| Post Translational Modifications | Reversibly palmitoylated. Palmitoylation at Cys-79 by DHHC2 is required for its trafficking from the ER to the plasma membrane and for its perinuclear localization. Increased phosphorylation during mitosis prevents binding to microtubules. |
| Function | High-affinity epithelial cell surface receptor for APF. Mediates the anchoring of the endoplasmic reticulum to microtubules. |
| Protein Name | Cytoskeleton-Associated Protein 463-Kda Cytoskeleton-Linking Membrane ProteinClimp-63P63 |
| Database Links | Reactome: R-MMU-381426Reactome: -MMU-5683826Reactome: -MMU-6798695Reactome: -MMU-8957275Reactome: -MMU-9696264Reactome: -MMU-9696270 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinCell MembraneCytoplasmCytoskeletonPerinuclear RegionTranslocates To The Perinuclear Region Upon Apf-Stimulation |
| Alternative Antibody Names | Anti-Cytoskeleton-Associated Protein 4 antibodyAnti-63-Kda Cytoskeleton-Linking Membrane Protein antibodyAnti-Climp-63 antibodyAnti-P63 antibodyAnti-Ckap4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
