Anti-CK-MB antibody [7502] (STJ400040)

SKU:
STJ400040

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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CK-MB is suitable for use in ELISA research applications.
Clonality: Monoclonal
Clone ID: 7502
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Purification: Purity accurate to greater than or equal to 95%
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: 18 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days OK +4 °C, 21 days OK +30 °C, 21 OK +35 °C, 21 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer.
Association Rate Constant: 8.9 x 105 1/Ms
Determination Method: SPR analysis (ProteOn XPR36)
Immunoreactivity: 80–120 % compared to the reference sample in an FIA test
Immunogen: human creatine kinase MB isoenzyme
Background Creatine kinase (CK) , also known as creatine phosphokinase (CPK) or phospho-creatine kinase is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. CK is often determined routinely in emergency patients. In addition, it is determined specifically in patients with chest pain and if acute renal failure is suspected. Elevation of CK is an indication of damage to muscle. It is therefore indicative of injury, rhabdomyolysis, myocardial infarction, muscular dystrophy, myositis, myocarditis, malignant hyperthermia, and neuroleptic malignant syndrome. Lowered CK can be an indication of alcoholic liver disease and rheumatoid arthritis.

Information sourced from Uniprot.org

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