| Function | Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. |
| Protein Name | Cdgsh Iron-Sulfur Domain-Containing Protein 2Endoplasmic Reticulum Intermembrane Small ProteinMitoneet-Related 1 ProteinMiner1Nutrient-Deprivation Autophagy Factor-1Naf-1 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinMitochondrion Outer MembraneIt Mainly Localizes To The Endoplasmic ReticulumHoweverExperiments In Mouse Showed That It Mainly Localizes To The Mitochondrion Outer Membrane |
| Alternative Antibody Names | Anti-Cdgsh Iron-Sulfur Domain-Containing Protein 2 antibodyAnti-Endoplasmic Reticulum Intermembrane Small Protein antibodyAnti-Mitoneet-Related 1 Protein antibodyAnti-Miner1 antibodyAnti-Nutrient-Deprivation Autophagy Factor-1 antibodyAnti-Naf-1 antibodyAnti-CISD2 antibodyAnti-CDGSH2 antibodyAnti-ERIS antibodyAnti-ZCD2 antibody |
Information sourced from Uniprot.org
