• Western blot analysis of lysates from HT-29 and RAW264.7 cells, using CIDEB Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of COS7 cells, using CIDEB Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human cervix caecinoma tissue, using CIDEB Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using CIDE-B Polyclonal Antibody

Anti-CIDEB antibody (91-140 aa) (STJ92293)

SKU:
STJ92293

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Lipid transferase CIDEB (91-140 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CIDEB
Gene ID: 27141
Uniprot ID: CIDEB_HUMAN
Immunogen Region: 91-140 aa
Specificity: CIDE-B Polyclonal Antibody detects endogenous levels of CIDE-B protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CIDEB at the amino acid range 91-140
Function Lipid transferase specifically expressed in hepatocytes, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Promotes lipid exchange and lipid droplet fusion in both small and large lipid droplet-containing hepatocytes. In addition to its role in lipid droplet fusion, also involved in cytoplasmic vesicle biogenesis and transport. Required for very-low-density lipoprotein (VLDL) lipidation and maturation. Probably involved in the biogenesis of VLDL transport vesicles by forming a COPII vesicle coat and facilitating the formation of endoplasmic reticulum-derived large vesicles. Also involved in sterol-regulated export of the SCAP-SREBP complex, composed of SCAP, SREBF1/SREBP1 and SREBF2/SREBP2, by promoting loading of SCAP-SREBP into COPII vesicles. May also activate apoptosis. (Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.
Protein Name Lipid Transferase Cideb
Cell Death Activator Cide-B
Cell Death-Inducing Dffa-Like Effector B
Cellular Localisation Lipid Droplet
Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Golgi Apparatus
Cytoplasmic Vesicle
Copi-Coated Vesicle
Enriched At Lipid Droplet Contact Sites
Alternative Antibody Names Anti-Lipid Transferase Cideb antibody
Anti-Cell Death Activator Cide-B antibody
Anti-Cell Death-Inducing Dffa-Like Effector B antibody
Anti-CIDEB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance