• Western blot analysis of lysates from NIH/3T3 cells, using CIC Rabbit polyclonal antibody (STJ117603) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-CIC antibody (1379-1608) (STJ117603)

SKU:
STJ117603

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CIC (1379-1608) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CIC
Gene ID: 23152
Uniprot ID: CIC_HUMAN
Immunogen Region: 1379-1608
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1379-1608 of human CIC (NP_055940.3).
Immunogen Sequence: LATSPRAILGSYRKKRKNST DLDSAPEDPTSPKRKMRRRS SCSSEPNTPKSAKCEGDIFT FDRTGTEAEDVLGELEYDKV PYSSLRRTLDQRRALVMQLF QDHGFFPSAQATAAFQARYA DIFPSKVCLQLKIREVRQKI MQAATPTEQPPGAEAPLPVP PPTGTAAAPAPTPSPAGGPD PTSPSSDSGTAQAAPPLPPP PESGPGQPGWEGAPQPSPPP PGPSTAATGR
Tissue Specificity Expressed in fetal brain.
Function Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.
Protein Name Protein Capicua Homolog
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Protein Capicua Homolog antibody
Anti-CIC antibody
Anti-KIAA0306 antibody

Information sourced from Uniprot.org

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