| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunogen Region: | 400-660 |
| Specificity: | Recombinant Protein corresponding to a sequence within amino acids 400-660 of rat CHUK (NP_001101058.1). |
| Immunogen Sequence: | SRSLSDCVNYIVQDSKIQLP VTQLRKVWAEAVHYVSGLKE DYSRLFQGQRAAMLSLLRYN ANLTKMKNTLISASQQLKAK LEFFRKSIQLDLERYSEQMT YGISSEKMLKAWKEMEEKAI HYSEVGVIGYLEDQIMSLHT EIMELQKSPYGRRQGDLMES LEQRAIDLYKQLKHRPTDHS YSDSTEMVKIIVHTVQSQDR VLKELFGHLSKLLGCKQKII DLLPKVEVALSNIKEADNT |
| Background | Contributes to IkappaB kinase activity. Involved in several processes, including Rho protein signal transduction; response to cholecystokinin; and response to lipopolysaccharide. Located in cytosol and intracellular membrane-bounded organelle. Part of IkappaB kinase complex. Used to study muscular atrophy. Biomarker of colitis. Human ortholog (s) of this gene implicated in fetal encasement syndrome and prostate cancer. Orthologous to human CHUK (component of inhibitor of nuclear factor kappa B kinase complex). |
Information sourced from Uniprot.org