Function | Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. |
Protein Name | Chondroitin Sulfate Synthase 1Chondroitin Glucuronyltransferase 1Chondroitin Synthase 1Chsy-1Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase 1N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase 1N-Acetylgalactosaminyltransferase 1 |
Database Links | Reactome: R-HSA-2022870Reactome: R-HSA-3595177 |
Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecreted |
Alternative Antibody Names | Anti-Chondroitin Sulfate Synthase 1 antibodyAnti-Chondroitin Glucuronyltransferase 1 antibodyAnti-Chondroitin Synthase 1 antibodyAnti-Chsy-1 antibodyAnti-Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase 1 antibodyAnti-N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase 1 antibodyAnti-N-Acetylgalactosaminyltransferase 1 antibodyAnti-CHSY1 antibodyAnti-CHSY antibodyAnti-CSS1 antibodyAnti-KIAA0990 antibodyAnti-UNQ756 antibodyAnti-PRO1487 antibody |
Information sourced from Uniprot.org