Anti-CHST2 antibody (1-50 aa) (STJ92285)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CHST2 at the amino acid range 1-50
General Information
| Short Description | Rabbit polyclonal anti-Carbohydrate sulfotransferase 2 (1-50 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHST2 |
| Gene ID | 9435 |
| Uniprot ID | CHST2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CHST2 at the amino acid range 1-50 |
| Immunogen Region | 1-50 aa |
| Specificity | CHST2 Polyclonal Antibody detects endogenous levels of CHST2 protein. |
Additional Info
| Post Translational Modifications | Glycosylation at Asn-475 is required for catalytic activity. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains. |
| Protein Name | Carbohydrate Sulfotransferase 2Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 2Gst-2N-Acetylglucosamine 6-O-Sulfotransferase 1Glcnac6st-1Gn6st-1 |
| Database Links | Reactome: R-HSA-2022854 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 2 antibodyAnti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 2 antibodyAnti-Gst-2 antibodyAnti-N-Acetylglucosamine 6-O-Sulfotransferase 1 antibodyAnti-Glcnac6st-1 antibodyAnti-Gn6st-1 antibodyAnti-CHST2 antibodyAnti-GN6ST antibody |
Information sourced from Uniprot.org