Post Translational Modifications | Glycosylated. |
Function | Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression.however such results are unclear in vivo. |
Protein Name | Carbohydrate Sulfotransferase 15B-Cell Rag-Associated Gene ProteinHbragN-Acetylgalactosamine 4-Sulfate 6-O-SulfotransferaseGalnac4s-6st |
Database Links | Reactome: R-HSA-2022870 |
Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinA Small Fraction May Also Be Present At The Cell SurfaceWhere It Acts As A B-Cell Receptor |
Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 15 antibodyAnti-B-Cell Rag-Associated Gene Protein antibodyAnti-Hbrag antibodyAnti-N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase antibodyAnti-Galnac4s-6st antibodyAnti-CHST15 antibodyAnti-BRAG antibodyAnti-GALNAC4S6ST antibodyAnti-KIAA0598 antibody |
Information sourced from Uniprot.org