| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-nAChR b4 (Cytoplasmic Loop) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: |
This antibody was antigen affinity purified from pooled serum. |
| Dilution Range: |
WB 1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Chrnb4 |
| Gene ID: |
108015 |
| Uniprot ID: |
ACHB4_MOUSE |
| Immunogen Region: |
Cytoplasmic Loop |
| Immunogen: |
Fusion protein from the cytoplasmic loop of the beta 4 subunit of rat nAChR. |
| Tissue Specificity | Predominantly expressed by immature T-cells in the thymus. |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Protein Name | Neuronal Acetylcholine Receptor Subunit Beta-4 |
| Database Links | Reactome: R-MMU-629587Reactome: -MMU-629594Reactome: -MMU-629597Reactome: -MMU-6798695 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Beta-4 antibodyAnti-Chrnb4 antibodyAnti-Acrb4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
