Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Neuronal acetylcholine receptor subunit alpha-9 (50-100 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CHRNA9 |
Gene ID: | 55584 |
Uniprot ID: | ACHA9_HUMAN |
Immunogen Region: | 50-100 aa |
Specificity: | AChR Alpha 9 Polyclonal Antibody detects endogenous levels of cholinergic receptor, nicotinic, alpha 9 |
Immunogen: | The antiserum was produced against synthesized peptide derived from the N-terminal region of human CHRNA9 at the amino acid range 50-100 |
Post Translational Modifications | N-glycosylated. |
Function | Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion. |
Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-9Nicotinic Acetylcholine Receptor Subunit Alpha-9Nachr Alpha-9 |
Database Links | Reactome: R-HSA-629594Reactome: R-HSA-9667769 |
Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Alpha-9 antibodyAnti-Nicotinic Acetylcholine Receptor Subunit Alpha-9 antibodyAnti-Nachr Alpha-9 antibodyAnti-CHRNA9 antibodyAnti-NACHRA9 antibody |
Information sourced from Uniprot.org