| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CHRNA4 (29-43) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000. WB: Approx 70kDa band observed in Rat Brain lysates (calculated MW of 70.0kDa according to Human NP_000735.1and of 70.2kDa according to Rat NP_077330.1). Recommended concentration: 1-3µg/m |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CHRNA4 |
| Gene ID: | 1137 |
| Uniprot ID: | ACHA4_HUMAN |
| Immunogen Region: | 29-43 |
| Accession Number: | NP_000735.1 |
| Specificity: | This antibody is expected NOT to cross-react with the similar alpha 2 subunit. |
| Immunogen Sequence: | HVETRAHAEERLLKK |
| Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-4 |
| Database Links | Reactome: R-HSA-629587 Reactome: R-HSA-629594 Reactome: R-HSA-629597 |
| Cellular Localisation | Postsynaptic Cell Membrane Multi-Pass Membrane Protein Cell Membrane Lipid-Anchor |
| Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Alpha-4 antibody Anti-CHRNA4 antibody Anti-NACRA4 antibody |
Information sourced from Uniprot.org