| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Neuronal acetylcholine receptor subunit alpha-3 (90-139 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHRNA3 |
| Gene ID: | 1136 |
| Uniprot ID: | ACHA3_HUMAN |
| Immunogen Region: | 90-139 aa |
| Specificity: | AChR Alpha 3 Polyclonal Antibody detects endogenous levels of AChR Alpha 3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human AChRalpha3 at the amino acid range 90-139 |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Protein Name | Neuronal Acetylcholine Receptor Subunit Alpha-3 |
| Database Links | Reactome: R-HSA-629587Reactome: R-HSA-629594Reactome: R-HSA-629597 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell MembraneEndoplasmic ReticulumGolgi ApparatusInteraction With Ubxn2a/Ubxd4 Promotes Translocation To The Plasma Membrane |
| Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Alpha-3 antibodyAnti-CHRNA3 antibodyAnti-NACHRA3 antibody |
Information sourced from Uniprot.org
