| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Chordin-like protein 2 (330-410 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHRDL2 |
| Gene ID: | 25884 |
| Uniprot ID: | CRDL2_HUMAN |
| Immunogen Region: | 330-410 aa |
| Specificity: | CRDL2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 330-410 |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation. |
| Protein Name | Chordin-Like Protein 2 Breast Tumor Novel Factor 1 Bnf-1 Chordin-Related Protein 2 |
| Cellular Localisation | Isoform 1: Secreted Isoform 2: Secreted Isoform 3: Cytoplasm Isoform 4: Cytoplasm Isoform 5: Cytoplasm |
| Alternative Antibody Names | Anti-Chordin-Like Protein 2 antibody Anti-Breast Tumor Novel Factor 1 antibody Anti-Bnf-1 antibody Anti-Chordin-Related Protein 2 antibody Anti-CHRDL2 antibody Anti-BNF1 antibody Anti-CHL2 antibody Anti-UNQ765 antibody Anti-PRO1557 antibody |
Information sourced from Uniprot.org