| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CHN2 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Preliminary experiments in Human Brain (Cerebellum and Frontal Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate a |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CHN2 |
| Gene ID: | 1124 |
| Uniprot ID: | CHIO_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_001035025.1; NP_004058.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_004058.1; NP_001035025.1). |
| Immunogen Sequence: | QILIENEDVLF |
| Function | GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors. |
| Protein Name | Beta-ChimaerinBeta-ChimerinRho Gtpase-Activating Protein 3 |
| Database Links | Reactome: R-HSA-9013149 |
| Cellular Localisation | MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Beta-Chimaerin antibodyAnti-Beta-Chimerin antibodyAnti-Rho Gtpase-Activating Protein 3 antibodyAnti-CHN2 antibodyAnti-ARHGAP3 antibodyAnti-BCH antibody |
Information sourced from Uniprot.org