| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHGB (1-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHGB |
| Gene ID: |
1114 |
| Uniprot ID: |
SCG1_HUMAN |
| Immunogen Region: |
1-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHGB (NP_001810.2). |
| Immunogen Sequence: |
MQPTLLLSLLGAVGLAAVNS MPVDNRNHNEGMVTRCIIEV LSNALSKSSAPPITPECRQV LKTSRKDVKDKETTENENTK FEVRLLRDPADASEAHESSS RGEAGAPGEEDIQGPTKADT EKWAEGGGHSRERADEPQWS LYPSDSQVSEEVKTRHSEKS QREDEEEEEGENYQKGERGE DSSEEKHLEEPGETQNAFLN ERKQASAIKKEELVARSETH AAGHSQEKTHSREKSSQES |
| Tissue Specificity | Detected in cerebrospinal fluid and urine (at protein level). Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. |
| Post Translational Modifications | Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues. O-glycosylated. |
| Function | Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. |
| Protein Name | Secretogranin-1Chromogranin-BCgbSecretogranin ISgi Cleaved Into - Pe-11 - Gawk Peptide - Ccb Peptide |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedNeuroendocrine And Endocrine Secretory Granules |
| Alternative Antibody Names | Anti-Secretogranin-1 antibodyAnti-Chromogranin-B antibodyAnti-Cgb antibodyAnti-Secretogranin I antibodyAnti-Sgi Cleaved Into - Pe-11 - Gawk Peptide - Ccb Peptide antibodyAnti-CHGB antibodyAnti-SCG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89098/357557/STJ11100026_1__69013.1713121681.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")