• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-CHD6 antibody (STJ190697)

SKU:
STJ190697

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Chromodomain-helicase-DNA-binding protein 6 is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHD6
Gene ID: 84181
Uniprot ID: CHD6_HUMAN
Specificity: CHD6 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. (Microbial infection) Acts as a transcriptional repressor of different viruses including influenza virus or papillomavirus. During influenza virus infection, the viral polymerase complex localizes CHD6 to inactive chromatin where it gets degraded in a proteasome independent-manner.
Protein Name Chromodomain-Helicase-Dna-Binding Protein 6
Chd-6
Atp-Dependent Helicase Chd6
Radiation-Induced Gene B Protein
Cellular Localisation Nucleus
Nucleoplasm
Enriched At Sites Of Mrna Synthesis
During Influenza A Virus Infection
Localizes To Inactive Chromatin
Alternative Antibody Names Anti-Chromodomain-Helicase-Dna-Binding Protein 6 antibody
Anti-Chd-6 antibody
Anti-Atp-Dependent Helicase Chd6 antibody
Anti-Radiation-Induced Gene B Protein antibody
Anti-CHD6 antibody
Anti-CHD5 antibody
Anti-KIAA1335 antibody
Anti-RIGB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance