Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CHD2 |
Gene ID: | 1106 |
Uniprot ID: | CHD2_HUMAN |
Immunogen Region: | 1-223 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human CHD2 (NP_001036037.1). |
Immunogen Sequence: | MMRNKDKSQEEDSSLHSNAS SHSASEEASGSDSGSQSESE QGSDPGSGHGSESNSSSESS ESQSESESESAGSKSQPVLP EAKEKPASKKERIADVKKMW EEYPDVYGVRRSNRSRQEPS RFNIKEEASSGSESGSPKRR GQRQLKKQEKWKQEPSEDEQ EQGTSAESEPEQKKVKARRP VPRRTVPKPRVKKQPKTQRG KRKKQDSSDEDDDDDEAPKR QTR |
Function | DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression. |
Protein Name | Chromodomain-Helicase-Dna-Binding Protein 2Chd-2Atp-Dependent Helicase Chd2 |
Cellular Localisation | NucleusBinds To Myogenic Gene Promoters |
Alternative Antibody Names | Anti-Chromodomain-Helicase-Dna-Binding Protein 2 antibodyAnti-Chd-2 antibodyAnti-Atp-Dependent Helicase Chd2 antibodyAnti-CHD2 antibody |
Information sourced from Uniprot.org