| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHCHD6 |
| Gene ID: | 84303 |
| Uniprot ID: | MIC25_HUMAN |
| Immunogen Region: | 1-235 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-235 of human CHCHD6 (NP_115719.1). |
| Immunogen Sequence: | MGSTESSEGRRVSFGVDEEE RVRVLQGVRLSENVVNRMKE PSSPPPAPTSSTFGLQDGNL RAPHKESTLPRSGSSGGQQP SGMKEGVKRYEQEHAAIQDK LFQVAKREREAATKHSKASL PTGEGSISHEEQKSVRLARE LESREAELRRRDTFYKEQLE RIERKNAEMYKLSSEQFHEA ASKMESTIKPRRVEPVCSGL QAQILHCYRDRPHEVLLCSD LVKAYQRCVSAAHKG |
| Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. |
| Protein Name | Micos Complex Subunit Mic25Coiled-Coil-Helix Cristae Morphology Protein 1Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion Inner MembraneLipid-AnchorMitochondrion |
| Alternative Antibody Names | Anti-Micos Complex Subunit Mic25 antibodyAnti-Coiled-Coil-Helix Cristae Morphology Protein 1 antibodyAnti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 6 antibodyAnti-CHCHD6 antibodyAnti-CHCM1 antibodyAnti-MIC25 antibody |
Information sourced from Uniprot.org