| Short Description : | Rabbit polyclonal CHAD (1-359) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHAD |
| Gene ID: | 1101 |
| Uniprot ID: | CHAD_HUMAN |
| Immunogen Region: | 1-359 |
| Immunogen Sequence: | MVRPMLLLSLGLLAGLLPAL AACPQNCHCHSDLQHVICDK VGLQKIPKVSEKTKLLNLQR NNFPVLAANSFRAMPNLVSL HLQHCQIREVAAGAFRGLKQ LIYLYLSHNDIRVLRAGAFD DLTELTYLYLDHNKVTELPR GLLSPLVNLFILQLNNNKIR ELRAGAFQGAKDLRWLYLSE NALSSLQPGALDDVENLAKF HVDRNQLSSYPSAALSKLRV VEELKLSHNPLKSIPDNAF |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human CHAD (NP_001258.2). |
| Tissue Specificity | Present in chondrocytes at all ages. |
| Function | Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation. |
| Protein Name | ChondroadherinCartilage Leucine-Rich Protein |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Chondroadherin antibodyAnti-Cartilage Leucine-Rich Protein antibodyAnti-CHAD antibodyAnti-SLRR4A antibody |
Information sourced from Uniprot.org
