Anti-CGI58/ABHD5 antibody (Internal) (STJ71112)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CGI58/ABHD5 (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IF/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 40kDa band observed in lysates of cell lines NIH3T3/3TL (calculated MW of 39.1kDa according to NP_057090.2). Additional faint bands of 26kDa and 18kDa were also observed, and we |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ABHD5 |
| Gene ID | 51099 |
| Uniprot ID | ABHD5_HUMAN |
| Accession Number | NP_057090.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | FPERPDLADQDR |
| Specificity | This antibody is not expected to cross-react with ABHD4. |
Additional Info
| Function | Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors. Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion. |
| Protein Name | 1-Acylglycerol-3-Phosphate O-Acyltransferase Abhd5Abhydrolase Domain-Containing Protein 5Lipid Droplet-Binding Protein Cgi-58 |
| Database Links | Reactome: R-HSA-163560 |
| Cellular Localisation | CytoplasmLipid DropletCytosolColocalized With Plin And Adrp On The Surface Of Lipid DropletsThe Localization Is Dependent Upon The Metabolic Status Of The Adipocytes And The Activity Of Pka |
| Alternative Antibody Names | Anti-1-Acylglycerol-3-Phosphate O-Acyltransferase Abhd5 antibodyAnti-Abhydrolase Domain-Containing Protein 5 antibodyAnti-Lipid Droplet-Binding Protein Cgi-58 antibodyAnti-ABHD5 antibodyAnti-NCIE2 antibodyAnti-CGI-58 antibody |
Information sourced from Uniprot.org