| Short Description : | Rabbit polyclonal CGB (21-165) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CGB3.CGB5.CGB8 |
| Gene ID: | 1082/93659/94115 |
| Uniprot ID: | CGB3_HUMAN |
| Immunogen Region: | 21-165 |
| Immunogen Sequence: | SKEPLRPRCRPINATLAVEK EGCPVCITVNTTICAGYCPT MTRVLQGVLPALPQVVCNYR DVRFESIRLPGCPRGVNPVV SYAVALSCQCALCRRSTTDC GGPKDHPLTCDDPRFQDSSS SKAPPPSLPSPSRLPGPSDT PILPQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-165 of human CGB (NP_000728.1). |
| Tissue Specificity | High expression in the placenta throughout pregnancy. |
| Function | Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. |
| Protein Name | Choriogonadotropin Subunit Beta 3Choriogonadotropin Subunit BetaCg-BetaChorionic Gonadotropin Chain Beta |
| Database Links | Reactome: R-HSA-209822Reactome: R-HSA-8866910 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Choriogonadotropin Subunit Beta 3 antibodyAnti-Choriogonadotropin Subunit Beta antibodyAnti-Cg-Beta antibodyAnti-Chorionic Gonadotropin Chain Beta antibodyAnti-CGB3 antibodyAnti-CGB.CGB5.CGB8 antibody |
Information sourced from Uniprot.org
