Anti-hCG beta antibody [5006] (STJ400082)

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STJ400082
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Host: Mouse
Applications: CLIA/FIA
Reactivity: hCG beta
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-hCG beta for use in CLIA and FIA in hCG beta samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 5006
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 0.9 % NaCI, 0.095 % NaN3 as a preservative
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: Store at 2–8 °C, and do not freeze.
Specificity: Antibody recognizes human chorionic gonadotropin and its free beta subunit. LH (KD = 24 nM). Does not recognize hCGa, FSH, or TSH
Immunogen: Beta-2 as described in Berger et al. (2013). The antibody recognizes both intact hCG and free ß subunit.
Tissue Specificity High expression in the placenta throughout pregnancy.
Function Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Protein Name Choriogonadotropin Subunit Beta 3
Choriogonadotropin Subunit Beta
Cg-Beta
Chorionic Gonadotropin Chain Beta
Database Links Reactome: R-HSA-209822
Reactome: R-HSA-8866910
Cellular Localisation Secreted
Alternative Antibody Names Anti-Choriogonadotropin Subunit Beta 3 antibody
Anti-Choriogonadotropin Subunit Beta antibody
Anti-Cg-Beta antibody
Anti-Chorionic Gonadotropin Chain Beta antibody
Anti-CGB3 antibody
Anti-CGB.CGB5.CGB8 antibody

Information sourced from Uniprot.org

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