Anti-CFP antibody (190-469) (STJ27351)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CFP (190-469) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CFP |
| Gene ID | 5199 |
| Uniprot ID | PROP_HUMAN |
| Immunogen Region | 190-469 |
| Immunogen Sequence | CPTHGAWATWGPWTPCSASC HGGPHEPKETRSRKCSAPEP SQKPPGKPCPGLAYEQRRCT GLPPCPVAGGWGPWGPVSPC PVTCGLGQTMEQRTCNHPVP QHGGPFCAGDATRTHICNTA VPCPVDGEWDSWGEWSPCIR RNMKSISCQEIPGQQSRGRT CRGRKFDGHRCAGQQQDIRH CYSIQHCPLKGSWSEWSTWG LCMPPCGPNPTRARQRLCTP LLPKYPPTVSMVEGQGEKN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1). |
Additional Info
| Function | A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). |
| Protein Name | ProperdinComplement Factor P |
| Database Links | Reactome: R-HSA-173736Reactome: R-HSA-174577Reactome: R-HSA-5083635Reactome: R-HSA-5173214Reactome: R-HSA-6798695Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Properdin antibodyAnti-Complement Factor P antibodyAnti-CFP antibodyAnti-PFC antibody |
Information sourced from Uniprot.org