| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CFHR5 |
| Gene ID: | 81494 |
| Uniprot ID: | FHR5_HUMAN |
| Immunogen Region: | 450-569 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-569 of human CFHR5 (NP_110414.1). |
| Immunogen Sequence: | GPPPSINNGDTTSFPLSVYP PGSTVTYRCQSFYKLQGSVT VTCRNKQWSEPPRCLDPCVV SEENMNKNNIQLKWRNDGKL YAKTGDAVEFQCKFPHKAMI SSPPFRAICQEGKFEYPICE |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. |
| Protein Name | Complement Factor H-Related Protein 5Fhr-5 |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement Factor H-Related Protein 5 antibodyAnti-Fhr-5 antibodyAnti-CFHR5 antibodyAnti-CFHL5 antibodyAnti-FHR5 antibody |
Information sourced from Uniprot.org