| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CFHR1 (151-330) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CFHR1 |
| Gene ID: |
3078 |
| Uniprot ID: |
FHR1_HUMAN |
| Immunogen Region: |
151-330 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 151-330 of human CFHR1 (NP_002104.2). |
| Immunogen Sequence: |
PTVQNAHILSRQMSKYPSGE RVRYECRSPYEMFGDEEVMC LNGNWTEPPQCKDSTGKCGP PPPIDNGDITSFPLSVYAPA SSVEYQCQNLYQLEGNKRIT CRNGQWSEPPKCLHPCVISR EIMENYNIALRWTAKQKLYL RTGESAEFVCKRGYRLSSRS HTLRTTCWDGKLEYPTCAKR |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | N-glycosylated. Two forms are observed.one with a single side chain and the other with two. |
| Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| Protein Name | Complement Factor H-Related Protein 1Fhr-1H Factor-Like Protein 1Fhl-1H-Factor-Like 1H36 |
| Database Links | Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement Factor H-Related Protein 1 antibodyAnti-Fhr-1 antibodyAnti-H Factor-Like Protein 1 antibodyAnti-Fhl-1 antibodyAnti-H-Factor-Like 1 antibodyAnti-H36 antibodyAnti-CFHR1 antibodyAnti-CFHL antibodyAnti-CFHL1 antibodyAnti-CFHL1P antibodyAnti-CFHR1P antibodyAnti-FHR1 antibodyAnti-HFL1 antibodyAnti-HFL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
