| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Complement Factor D (26-253) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4181RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CFD |
| Gene ID: |
1675 |
| Uniprot ID: |
CFAD_HUMAN |
| Immunogen Region: |
26-253 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human CFD (P00746). |
| Immunogen Sequence: |
ILGGREAEAHARPYMASVQL NGAHLCGGVLVAEQWVLSAA HCLEDAADGKVQVLLGAHSL SQPEPSKRLYDVLRAVPHPD SQPDTIDHDLLLLQLSEKAT LGPAVRPLPWQRVDRDVAPG TLCDVAGWGIVNHAGRRPDS LQHVLLPVLDRATCNRRTHH DGAITERLMCAESNRRDSCK GDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYA AWIDSVLA |
| Function | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. |
| Protein Name | Complement Factor DAdipsinC3 Convertase ActivatorProperdin Factor D |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-173736Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement Factor D antibodyAnti-Adipsin antibodyAnti-C3 Convertase Activator antibodyAnti-Properdin Factor D antibodyAnti-CFD antibodyAnti-DF antibodyAnti-PFD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
