| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CETP |
| Gene ID: | 1071 |
| Uniprot ID: | CETP_HUMAN |
| Immunogen Region: | 300-493 |
| Immunogen Sequence: | LMLSLMGDEFKAVLETWGFN TNQEIFQEVVGGFPSQAQVT VHCLKMPKISCQNKGVVVNS SVMVKFLFPRPDQQHSVAYT FEEDIVTTVQASYSKKKLFL SLLDFQITPKTVSNLTESSS ESVQSFLQSMITAVGIPEVM SRLEVVFTALMNSKGVSLFD IINPEIITRDGFLLLQMDFG FPEHLLVDFLQSLS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-493 of human CETP (NP_000069.2). |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Function | Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination. |
| Protein Name | Cholesteryl Ester Transfer ProteinLipid Transfer Protein I |
| Database Links | Reactome: R-HSA-8964041Reactome: R-HSA-8964058Reactome: R-HSA-9029569 |
| Cellular Localisation | SecretedSecreted In Plasma |
| Alternative Antibody Names | Anti-Cholesteryl Ester Transfer Protein antibodyAnti-Lipid Transfer Protein I antibodyAnti-CETP antibody |
Information sourced from Uniprot.org
