| Short Description : | Rabbit polyclonal anti-Centrosomal protein of 192 kDa for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEP192 |
| Gene ID: | 55125 |
| Uniprot ID: | CE192_HUMAN |
| Immunogen: | Synthesized peptide derived from human CEP192 |
| Specificity: | This antibody detects endogenous levels of CEP192 at Human |
| Function | Required for mitotic centrosome maturation and bipolar spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Centrosome-specific activating scaffold for AURKA and PLK1. |
| Protein Name | Centrosomal Protein Of 192 KdaCep192Cep192/Spd-2 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentriolePericentriolar Location In Mitotic Centrosomes |
| Alternative Antibody Names | Anti-Centrosomal Protein Of 192 Kda antibodyAnti-Cep192 antibodyAnti-Cep192/Spd-2 antibodyAnti-CEP192 antibodyAnti-KIAA1569 antibodyAnti-PP8407 antibody |
Information sourced from Uniprot.org
