Anti-CENPI antibody (10-90 aa) (STJ191680)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 10-90
General Information
| Short Description | Rabbit polyclonal anti-Centromere protein I (10-90 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CENPI |
| Gene ID | 2491 |
| Uniprot ID | CENPI_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 10-90 |
| Immunogen Region | 10-90 aa |
| Specificity | CENPI Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. |
| Protein Name | Centromere Protein ICenp-IFsh Primary Response Protein 1Follicle-Stimulating Hormone Primary Response ProteinInterphase Centromere Complex Protein 19Leucine-Rich Primary Response Protein 1 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-606279Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusChromosomeCentromereLocalizes Exclusively In The CentromeresThe Cenpa-Cad Complex Is Probably Recruited On Centromeres By The Cenpa-Nac Complex |
| Alternative Antibody Names | Anti-Centromere Protein I antibodyAnti-Cenp-I antibodyAnti-Fsh Primary Response Protein 1 antibodyAnti-Follicle-Stimulating Hormone Primary Response Protein antibodyAnti-Interphase Centromere Complex Protein 19 antibodyAnti-Leucine-Rich Primary Response Protein 1 antibodyAnti-CENPI antibodyAnti-FSHPRH1 antibodyAnti-ICEN19 antibodyAnti-LRPR1 antibody |
Information sourced from Uniprot.org