| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Carcinoembryonic antigen-related cell adhesion molecule 6 (100-150 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEACAM6 |
| Gene ID: | 4680 |
| Uniprot ID: | CEAM6_HUMAN |
| Immunogen Region: | 100-150 aa |
| Specificity: | CEAM6 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 100-150 |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells. |
| Protein Name | Cell Adhesion Molecule Ceacam6 Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 Cea Cell Adhesion Molecule 6 Non-Specific Crossreacting Antigen Normal Cross-Reacting Antigen Cd Antigen Cd66c |
| Database Links | Reactome: R-HSA-1566977 Reactome: R-HSA-202733 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Apical Cell Membrane Cell Surface Localized To The Apical Glycocalyx Surface |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Ceacam6 antibody Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 antibody Anti-Cea Cell Adhesion Molecule 6 antibody Anti-Non-Specific Crossreacting Antigen antibody Anti-Normal Cross-Reacting Antigen antibody Anti-Cd Antigen Cd66c antibody Anti-CEACAM6 antibody Anti-NCA antibody |
Information sourced from Uniprot.org