| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Carcinoembryonic antigen-related cell adhesion molecule 5 (481-530 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:100-300 ELISA 1:20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CEACAM5 |
| Gene ID: | 1048 |
| Uniprot ID: | CEAM5_HUMAN |
| Immunogen Region: | 481-530 aa |
| Specificity: | CD66e Polyclonal Antibody detects endogenous levels of CD66e protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM5 at the amino acid range 481-530 |
| Post Translational Modifications | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. |
| Protein Name | Cell Adhesion Molecule Ceacam5 Carcinoembryonic Antigen Cea Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Cea Cell Adhesion Molecule 5 Meconium Antigen 100 Cd Antigen Cd66e |
| Database Links | Reactome: R-HSA-163125 Reactome: R-HSA-202733 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Apical Cell Membrane Cell Surface Localized To The Apical Glycocalyx Surface |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Ceacam5 antibody Anti-Carcinoembryonic Antigen antibody Anti-Cea antibody Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 antibody Anti-Cea Cell Adhesion Molecule 5 antibody Anti-Meconium Antigen 100 antibody Anti-Cd Antigen Cd66e antibody Anti-CEACAM5 antibody Anti-CEA antibody |
Information sourced from Uniprot.org