| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDX1 (136-265) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDX1 |
| Gene ID: |
1044 |
| Uniprot ID: |
CDX1_HUMAN |
| Immunogen Region: |
136-265 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 136-265 of human CDX1 (NP_001795.2). |
| Immunogen Sequence: |
MRRSVAAGGGGGSGKTRTKD KYRVVYTDHQRLELEKEFHY SRYITIRRKSELAANLGLTE RQVKIWFQNRRAKERKVNKK KQQQQQPPQPPMAHDITATP AGPSLGGLCPSNTSLLATSS PMPVKEEFLP |
| Tissue Specificity | Intestinal epithelium. |
| Function | Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA. |
| Protein Name | Homeobox Protein Cdx-1Caudal-Type Homeobox Protein 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Cdx-1 antibodyAnti-Caudal-Type Homeobox Protein 1 antibodyAnti-CDX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
