Anti-Cdx1 antibody (1-100) [S2MR] (STJ11103662)

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STJ11103662
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S2MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDX1
Gene ID: 1044
Uniprot ID: CDX1_HUMAN
Immunogen Region: 1-100
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cdx1 (P47902).
Immunogen Sequence: MYVGYVLDKDSPVYPGPARP ASLGLGPQAYGPPAPPPAPP QYPDFSSYSHVEPAPAPPTA WGAPFPAPKDDWAAAYGPGP AAPAASPASLAFGPPPDFSP
Tissue Specificity Intestinal epithelium.
Function Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Protein Name Homeobox Protein Cdx-1
Caudal-Type Homeobox Protein 1
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Cdx-1 antibody
Anti-Caudal-Type Homeobox Protein 1 antibody
Anti-CDX1 antibody

Information sourced from Uniprot.org