| Tissue Specificity | Widely expressed. Expressed in heart, brain and retina, and to a lesser extent in placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. |
| Protein Name | Phosphatidate Cytidylyltransferase 2Cdp-Dag Synthase 2Cdp-Dg Synthase 2Cdp-Diacylglycerol Synthase 2Cds 2Cdp-Diglyceride Pyrophosphorylase 2Cdp-Diglyceride Synthase 2Ctp -Phosphatidate Cytidylyltransferase 2 |
| Database Links | Reactome: R-HSA-1483148 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phosphatidate Cytidylyltransferase 2 antibodyAnti-Cdp-Dag Synthase 2 antibodyAnti-Cdp-Dg Synthase 2 antibodyAnti-Cdp-Diacylglycerol Synthase 2 antibodyAnti-Cds 2 antibodyAnti-Cdp-Diglyceride Pyrophosphorylase 2 antibodyAnti-Cdp-Diglyceride Synthase 2 antibodyAnti-Ctp -Phosphatidate Cytidylyltransferase 2 antibodyAnti-CDS2 antibody |
Information sourced from Uniprot.org
