| Host: |
Rabbit |
| Applications: |
ELISA/WB/IF/IHC-P |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDNF is suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
50% saturated ammonium sulphate in PBS pH 7.4 |
| Purification: |
CDNF-affinity purification |
| Dilution Range: |
ELISA 0.1 to 0.2 µg/ml; WB 0.1 to 0.2 µg/ml; IF 0.3 to 2 µg/mlIHC-P (on formalin-fixed, paraffin-embedded tissues, antigen retrieval)-5 to 10 µg/ml;Monoclonal antibody working dilution has to be established practically for each particular antigen and |
| Storage Instruction: |
Store at +4°C upon receipt. As product is (NH4) 2SO4 precipitate, mix well by pipetting or vortexing prior use |
| Gene Symbol: |
CDNF |
| Gene ID: |
441549 |
| Uniprot ID: |
CDNF_HUMAN |
| Specificity: |
Human, mouse; others not tested |
| Immunogen: |
Recombinant human CDNF protein produced using CHO-based proprietary suspension cell line. Purified from cell culture supernatant. . Human CDNF |
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerebral Dopamine Neurotrophic Factor antibodyAnti-Armet-Like Protein 1 antibodyAnti-Conserved Dopamine Neurotrophic Factor antibodyAnti-CDNF antibodyAnti-ARMETL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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