| Host: |
Mouse |
| Applications: |
ELISA/WB/IF/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CDNF (126-187 aa) is suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
6G5 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
PBS pH 7.4, with 0.1% sodium azide |
| Purification: |
Protein G purified |
| Dilution Range: |
ELISA-0.06 to 0.2 µg/ml; WB-0.25 to 1 µg/ml; IF-0.3 to 10 µg/ml; IHC (on formalin-fixed, paraffin-embedded tissues, antigen retrieval)-5 to 10 µg/ml; Monoclonal antibody working titer has to be established practically for each particular antigen and |
| Storage Instruction: |
Store at-20 or-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result. |
| Gene Symbol: |
CDNF |
| Gene ID: |
441549 |
| Uniprot ID: |
CDNF_HUMAN |
| Immunogen Region: |
126-187 aa |
| Specificity: |
Human, no reactivity with mouse CDNFBinds to the C-terminal part of the human CDNF (aa 126-187) |
| Immunogen: |
Recombinant human CDNF protein produced using CHO-based proprietary suspension cell line. Purified from cell culture supernatant. Binds C-terminal part of the human CDNF (aa 126-187) |
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerebral Dopamine Neurotrophic Factor antibodyAnti-Armet-Like Protein 1 antibodyAnti-Conserved Dopamine Neurotrophic Factor antibodyAnti-CDNF antibodyAnti-ARMETL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-CDNF antibody (25-125 aa) [7D6] (STJA0002818)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/150084/299799/STJA0002818_1__78535.1633363898.jpg?c=1 "Anti-CDNF antibody (25-125 aa) [7D6] (STJA0002818)")
