| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CDKAL1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: This antibody has been described in a publication and it has been successfully used on Human islets and pancreatic insulinoma INS-1 and MIN6 cells. Preliminary experiments gave an appr |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CDKAL1 |
| Gene ID: | 54901 |
| Uniprot ID: | CDKAL_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_060244.2 |
| Immunogen Sequence: | QVKKQRTKDLSR |
| Function | Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. |
| Protein Name | Threonylcarbamoyladenosine Trna MethylthiotransferaseCdk5 Regulatory Subunit-Associated Protein 1-Like 1Trna-T(6a37 Methylthiotransferase |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinIs A Tail-Anchored Protein That Exploits The Tcr40 Pathway For Insertion Into The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Threonylcarbamoyladenosine Trna Methylthiotransferase antibodyAnti-Cdk5 Regulatory Subunit-Associated Protein 1-Like 1 antibodyAnti-Trna-T(6a37 Methylthiotransferase antibodyAnti-CDKAL1 antibody |
Information sourced from Uniprot.org