Anti-CDK5RAP1 antibody (251-300 aa) (STJ92201)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CDK5RAP1 at the amino acid range 251-300
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial tRNA methylthiotransferase CDK5RAP1adenosine37 methylthiotransferase (251-300 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagent |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDK5RAP1 |
| Gene ID | 51654 |
| Uniprot ID | CK5P1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CDK5RAP1 at the amino acid range 251-300 |
| Immunogen Region | 251-300 aa |
| Specificity | CDK5 Activator-binding C42 Polyclonal Antibody detects endogenous levels of CDK5 Activator-binding C42 protein. |
Additional Info
| Function | Methylthiotransferase that catalyzes the conversion of N6-(dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp). Essential for efficient and highly accurate protein translation by the ribosome. Specifically inhibits CDK5 activation by CDK5R1. Essential for efficient mitochondrial protein synthesis and respiratory chain.shows pathological consequences in mitochondrial disease. |
| Protein Name | Mitochondrial Trna Methylthiotransferase Cdk5rap1Cdk5 Activator-Binding Protein C42Cdk5 Regulatory Subunit-Associated Protein 1Mt-Trna-2-Methylthio-N6-Dimethylallyladenosine SynthaseMt-Trna-N6-(Dimethylallyladenosine(37 Methylthiotransferase |
| Database Links | |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Mitochondrial Trna Methylthiotransferase Cdk5rap1 antibodyAnti-Cdk5 Activator-Binding Protein C42 antibodyAnti-Cdk5 Regulatory Subunit-Associated Protein 1 antibodyAnti-Mt-Trna-2-Methylthio-N6-Dimethylallyladenosine Synthase antibodyAnti-Mt-Trna-N6-(Dimethylallyladenosine(37 Methylthiotransferase antibodyAnti-CDK5RAP1 antibodyAnti-C20orf34 antibodyAnti-CGI-05 antibodyAnti-HSPC167 antibody |
Information sourced from Uniprot.org