| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cyclin-dependent kinase 13 (650-730 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDK13 |
| Gene ID: |
8621 |
| Uniprot ID: |
CDK13_HUMAN |
| Immunogen Region: |
650-730 aa |
| Specificity: |
CDK13 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 650-730 |
| Function | Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef. |
| Protein Name | Cyclin-Dependent Kinase 13Cdc2-Related Protein Kinase 5Cell Division Cycle 2-Like Protein Kinase 5Cell Division Protein Kinase 13Hcdk13Cholinesterase-Related Cell Division Controller |
| Database Links | Reactome: R-HSA-6796648Reactome: R-HSA-6798695 |
| Cellular Localisation | Nucleus Speckle |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 13 antibodyAnti-Cdc2-Related Protein Kinase 5 antibodyAnti-Cell Division Cycle 2-Like Protein Kinase 5 antibodyAnti-Cell Division Protein Kinase 13 antibodyAnti-Hcdk13 antibodyAnti-Cholinesterase-Related Cell Division Controller antibodyAnti-CDK13 antibodyAnti-CDC2L antibodyAnti-CDC2L5 antibodyAnti-CHED antibodyAnti-KIAA1791 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
