Anti-CDHR2 antibody (STJA0008007)

SKU:
STJA0008007
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Cadherin-related family member 2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDHR2
Gene ID: 54825
Uniprot ID: CDHR2_HUMAN
Specificity: This antibody detects endogenous levels of PCDH24 at Human
Immunogen: Synthesized peptide derived from human PCDH24
Function Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.
Protein Name Cadherin-Related Family Member 2
Protocadherin Lkc
Pc-Lkc
Protocadherin-24
Cellular Localisation Apical Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Microvillus Membrane
Cell Junction
Alternative Antibody Names Anti-Cadherin-Related Family Member 2 antibody
Anti-Protocadherin Lkc antibody
Anti-Pc-Lkc antibody
Anti-Protocadherin-24 antibody
Anti-CDHR2 antibody
Anti-PCDH24 antibody
Anti-PCLKC antibody

Information sourced from Uniprot.org

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