| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CDH13/H-cadherin (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000. WB: Approx 110kDa band observed in Human Heart lysates and 85kDa in Human Brain (Amygdala and Hippocampus) lysates (calculated MW of 78.3kDa according to NP_001248.1). The observed molecula |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CDH13 |
| Gene ID: | 1012 |
| Uniprot ID: | CAD13_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001248.1; NP_001207417.1; NP_001207418.1 |
| Specificity: | The immunizing peptide represents the N terminus of the mature protein. This antibody is expected to recognize isoform 1, 2 and 3 (NP_001248.1; NP_001207417.1; NP_001207418.1). |
| Immunogen Sequence: | DSDRPERSKFRLTGK |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
| Protein Name | Cadherin-13 Heart Cadherin H-Cadherin P105 Truncated Cadherin T-Cad T-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Cytoplasm |
| Alternative Antibody Names | Anti-Cadherin-13 antibody Anti-Heart Cadherin antibody Anti-H-Cadherin antibody Anti-P105 antibody Anti-Truncated Cadherin antibody Anti-T-Cad antibody Anti-T-Cadherin antibody Anti-CDH13 antibody Anti-CDHH antibody |
Information sourced from Uniprot.org