| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CDH13/H cadherin (285-297) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 125kDa band observed in Human Heart lysates (calculated MW of 83.4kDa according to NP_001207417.1). The observed molecular weight corresponds to earlier findings in literature |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CDH13 |
| Gene ID: | 1012 |
| Uniprot ID: | CAD13_HUMAN |
| Immunogen Region: | 285-297 |
| Accession Number: | NP_001248.1; NP_001207417.1; NP_001207418.1, NP_001207419.1 |
| Specificity: | This antibody is expected to recognize isoform 1, 2, 3 and 4 (NP_001248.1; NP_001207417.1; NP_001207418.1; NP_001207419.1). |
| Immunogen Sequence: | NIRQQTPDKPSPN |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
| Protein Name | Cadherin-13Heart CadherinH-CadherinP105Truncated CadherinT-CadT-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCytoplasm |
| Alternative Antibody Names | Anti-Cadherin-13 antibodyAnti-Heart Cadherin antibodyAnti-H-Cadherin antibodyAnti-P105 antibodyAnti-Truncated Cadherin antibodyAnti-T-Cad antibodyAnti-T-Cadherin antibodyAnti-CDH13 antibodyAnti-CDHH antibody |
Information sourced from Uniprot.org