| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDH11 (637-796) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDH11 |
| Gene ID: |
1009 |
| Uniprot ID: |
CAD11_HUMAN |
| Immunogen Region: |
637-796 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 637-796 of human CDH11 (NP_001788.2). |
| Immunogen Sequence: |
FVTLRRQKKEPLIVFEEEDV RENIITYDDEGGGEEDTEAF DIATLQNPDGINGFIPRKDI KPEYQYMPRPGLRPAPNSVD VDDFINTRIQEADNDPTAPP YDSIQIYGYEGRGSVAGSLS SLESATTDSDLDYDYLQNWG PRFKKLADLYGSKDTFDDDS |
| Tissue Specificity | Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. In the embryo from 67 to 72 days of gestation, detected at high levels in facial mesenchyme including the central palatal mesenchyme, dental mesenchyme, the eye and optic muscle, and the tongue (at protein level). |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. Required for proper focal adhesion assembly. Involved in the regulation of cell migration. |
| Protein Name | Cadherin-11Osf-4Osteoblast CadherinOb-Cadherin |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-9759811 P55287-2Reactome: R-HSA-9762292 P55287-2Reactome: R-HSA-9833576 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-11 antibodyAnti-Osf-4 antibodyAnti-Osteoblast Cadherin antibodyAnti-Ob-Cadherin antibodyAnti-CDH11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
