| Host: | Rabbit |
| Applications: | WB/IHC-P/ICC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-CDC6 for use in WB, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R03-5K5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CDC6 |
| Gene ID: | 990 |
| Uniprot ID: | CDC6_HUMAN |
| Immunogen: | A synthesized peptide derived from human Cdc6 |
| Post Translational Modifications | Ubiquitinated by the SCF(CCNF) E3 ubiquitin-protein ligase complex. |
| Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
| Protein Name | Cell Division Control Protein 6 HomologCdc6-Related ProteinCdc18-Related ProteinHscdc18P62(Cdc6Hscdc6 |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-176187Reactome: R-HSA-68689Reactome: R-HSA-68867Reactome: R-HSA-68949Reactome: R-HSA-68962Reactome: R-HSA-69017Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmThe Protein Is Nuclear In G1 And Cytoplasmic In S-Phase Cells |
| Alternative Antibody Names | Anti-Cell Division Control Protein 6 Homolog antibodyAnti-Cdc6-Related Protein antibodyAnti-Cdc18-Related Protein antibodyAnti-Hscdc18 antibodyAnti-P62(Cdc6 antibodyAnti-Hscdc6 antibodyAnti-CDC6 antibodyAnti-CDC18L antibody |
Information sourced from Uniprot.org
